Modeling the tumor microenvironment using chitosan-alginate scaffolds to control the stem-like state of glioblastoma cells.
نویسندگان
چکیده
Better prediction of in vivo drug efficacy using in vitro models should greatly improve in vivo success. Here we utilize 3D highly porous chitosan-alginate complex scaffolds to probe how various components of the glioblastoma microenvironment including extracellular matrix and stromal cells affect tumor cell stem-like state.
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عنوان ژورنال:
- Biomaterials science
دوره 4 4 شماره
صفحات -
تاریخ انتشار 2016